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Study: Antiviral protein may fight Ebola

Posted by tumicrobiology on March 20, 2007

German scientists have found an antiviral protein shown to inhibit other viruses might protect against Ebola and Marburg virus infections.

The Ebola and Marburg viruses belong to the Filoviridae family and cause severe hemorrhagic fever in humans and non-human primates. Filovirus infections are characterized by high fever, hemorrhages and shock and are responsible for mortality rates up to 90 percent. Currently, there is no vaccine or therapy available for treating infected patients.

In a previous study researchers found the zinc finger antiviral protein, or ZAP, capable of inhibiting Moloney murine leukemia virus and Sindbis virus replication.

In the new study, ZAP was tested for its antiviral activity in cells infected with Ebola and Marburg. Results showed up to 95 percent inhibition of Ebola, while Marburg was less significantly inhibited suggesting the antiviral effectiveness of ZAP may depend on the filovirus species.

The study conducted at the Bernhard-Nocht Institute for Tropical Medicine in Hamburg is reported in the Journal of Virology.


4 Responses to “Study: Antiviral protein may fight Ebola”

  1. lky said

    it is very nice to see such websites on microbiology.please enroll the list of worlds top microbiology colleges wishes 4 ur progess

  2. zapper01 said

    What I find to be a shame is that microbiology constantly leans to the drugs and ignores such advanced technology such as LVPEF which can rip microbes apart in a matter of a few minutes. Meanwhile, people are dying unnecessarily on a daily basis.

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    Study: Antiviral protein may fight Ebola « See the World through Microscopic Perspective

  4. Yakthungba said

    nice post

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